医師紹介

手術経験数の合計（1995～2020年）

1. 心臓血管外科 総手術経験数 ：3000例
2. 開心術・大血管手術経験数 ：2600例（小児1000例、成人1600例）
3. 開心術・大血管手術執刀数 ：1500例（先天性200例、後天性1300例）

手術成績（自身の手術死亡率は2011-2020年。学会発表主要施設死亡率は2019年時点）

冠動脈バイパス術	手術死亡3/360(0.83%)	学会発表 2.87%
大動脈弁置換術	手術死亡0/101(0.00%)	学会発表 4.36%
僧帽弁手術	手術死亡2/165(1.21%)	学会発表 4.81%
A型急性大動脈解離	手術死亡5/100(5.00%)	学会発表 12.27%
心室中隔欠損症	手術死亡0/56(0.00%)	学会発表 3.28%

診療実績の特徴

一般外科研修を終えた後、榊原記念病院や福岡こども病院などで心臓血管手術修練を積みました。その後英国ブリストル大学でRegistrarの資格を取り、3年間（1997～2000年）で行った約800例の手術トレーニングが心臓血管外科医としての基礎となりました。心臓血管外科には先天性心疾患、虚血性心疾患、弁膜症、大動脈疾患の分野があり、多くの心臓血管外科医は自分の分野を1つに定める傾向にあります。当初私は小児先天性心臓手術を専門とするべく修練してきましたが、2002年以降は成人心疾患手術の修練も積み重ね、最終的には大人と子供両方の心臓手術を行う、世界的にも数少ない心臓外科医の一人として執刀してきました。小児、大人を問わず、何れにおいても十分な手術経験があり、こうした経験が患者様の全身状態の把握や問題点の抽出、治療法の決定といった、診療上最も大切な”医師の能力”の根幹を支えています。

論文

※英語論文の内、筆頭著者(first author)と研究且つ論文責任者(corresponding author又はそれに相当する立場)のものだけの表記とさせていただいています。

掲載誌：Circulation

1. Imura H, Caputo M, Parry A, Pawade A, Angelini GD, Suleiman MS. Age-dependent and hypoxia-related differences in myocardial protection during pediatric open heart surgery. Circulation 103: 1551-1556. 2001.
2. Imura H, Nitta T, Sakamoto S, Shimizu K, Ochi M. Interactive pathologies of mitral prolapse and “true” membranous septal aneurysm with a valve-like structure. Circulation. 126, 3095-96. 2012.

掲載誌：Journal of Thoracic and Cardiovascular Surgery

1. Imura H, Duncan HP, Corfield AP, Myerscough N, Caputo M, Angelini GD, Wolf AR, Henderson AJ. Increased airway mucins after cardiopulmonary bypass associated with postoperative respiratory complications in children. J Thorac Cardiovasc Surg 127: 963-969. 2004.
2. Imura H, Caputo M, Lim K, Ochi M, Suleiman MS, Shimizu K, Angelini GD. Pulmonary injury after cardiopulmonary bypass: beneficial effects of low frequency mechanical ventilation. J Thorac Cardiovasc Surg 137: 1530-7. 2009.
3. Imura H, Lin H, Griffith EJ, Suleiman MS. Controlled hyperkalemic reperfusion with magnesium rescues ischemic juvenile hearts by reducing calcium loading. J Thorac Cardiovasc Surg 141: 1629-37. 2011.
4. Imura H, Ascione R, Angelini GD. Lung ventilation/perfusion may reduce pulmonary injury during cardiopulmonary bypass. J Thorac Cardiovasc Surg, 139, 236-7. 2010.
5. Modi P, Imura H, Caputo M, Pawade A, Parry AJ, Angelini GD, Suleiman MS. Cardiopulmonary bypass-induced myocardial reoxygenation injury in pediatric patients with cyanosis. J Thorac Cardiovasc Surg 124: 1035-6. 2002. (研究責任及び指導論文)

掲載誌：Annals of Thoracic Surgery

1. Imura H, Sakamoto S, Maruyama Y, Ochi M, Shimizu K. Two-patch repair for atrioventricular septal defect with mitral aneurysm. Ann Thorac Surg, 88: 1341-3. 2009.
2. Imura H, Modi P, Pawade A, Parry A, Suleiman MS, Angelini GD, Caputo M. Cardiac troponin I in neonates undergoing the arterial switch operation. Ann Thorac Surg 74: 1998-2002. 2002.
3. Caputo M, Modi P, Imura H, Pawade A, Parry AJ, Suleiman MS, Angelini GD. Cold blood versus cold crystalloid cardioplegia for repair of ventricular septal defects in pediatric heart surgery: a randomized controlled trial. Ann Thorac Surg 74: 530-4. 2002. (研究責任及び指導論文)
4. Ascione R, Iannnelli G, Lim KH, Imura H, Spampinato N. One-staged coronary and abdominal aortic operation with or without cardiopulmonary bypass: early and midterm follow-up. Ann Thorac Surg 72: 768-74. 2001. （指導論文）

掲載誌：その他

1. Imura H, Suleiman MS. Cardioprotection of neonatal heart using normothermic hyperkalemia: the importance of delivery and terminal cardioplegia. Mol Cell Biochem 310: 1-9. 2008.
2. Imura H, Ayres BE, Suleiman MS. Purine metabolism and release during cardioprotection with hyperkalemia and hypothermia. Mol Cell Biochem 237: 119-127. 2002.
3. Murata T, Maeda M, Amitani R, Hiromoto A, Shirakawa M, Kambe M, Maruyama Y, Imura H. Postoperative changes in pulmonary function after valve surgery: Oxygenation index early after cardiopulmonary bypass is as predictor of postoperative course. J Clin Med 10: 3262. 2021. (Corresponding Author)
4. Hiromoto A, Maeda M, Murata T, Shirakawa M, Okamoto J, Maruyama Y, Imura H. Early extubation in current valve surgery requiring long cardiopulmonary bypass: Benefits and predictive value of preoperative spirometry. Heart &Lung 49: 709-15. 2020. (Corresponding Author)
5. Shirakawa M, Imura H, Nitta T. Propofol protects the immature rabbit heart against ischemia and reperfusion injury: impact on functional recovery and histopathological changes. Biomed Res Int 2014: 601250. 2014. (Corresponding Author, 学位指導)
6. Imura H, Maruyama Y, Shirakawa M, Nitta T. Long-term impacts of critical silent cerebrovascular disease in patients undergoing coronary artery bypass surgery: a propensity score and multivariate analyses. Perfusion 34: 147-153. 2019.
7. Imura H, Tanoue M, Shibata M, Maruyama Y, Shirakawa M, Ochi M. Acute type-A aortic dissection with patent false lumen through to the abdominal aorta: effects of conventional elephant trunk on mal-perfusion syndromes and narrowed true lumen. Perfusion 29: 417-424. 2014.
8. Imura H, Yuji Maruyama, Kenichiro Takahashi, Dai Nishina, Takashi Nitta. Coronary artery bypass surgery in patients with chronic brain hypoperfusion. J Cardiovasc Surg 59: 640-647. 2018.
9. Modi P, Imura H, Angelini GD, Pawade A, Parry AJ, Suleiman MS, Caputo M. Pathology-related troponin I release and clinical outcome after pediatric open heart surgery. J Card Surg 18: 295-300. 2003. (研究責任及び指導論文)
10. Imura H, Shirakawa M, Takahashi K, Maeda M, Yosio T, Maruyama Y, Nitta T. Coronary artery bypass grafting with complete revascularization can provide equivalent long-term prevention of ischemic cardiac event for patients on and not on hemodialysis: a graft-matched and baseline adjusted analysis. Surgical Science 9: 367-380. 2018.
11. Imura H, Yuji Maruyama, Makoto Shirakawa, Takashi Nitta. Impact of perioperative management for intracranial arterial stenosis on postoperative stroke incidence in coronary artery bypass surgery: a propensity matching and multivariate analyses. Surgical Science 9: 311-324. 2018.
12. Imura H, Nishina D, Maruyama Y, Shirakawa M, Tanoue M, Suzuki D, Yoshio T, Ochi M. Coronary artery bypass surgery for patients with severe cerebrovascular atherosclerosis: importance of preoperative assessment and perioperative management. Surgical Science 4: 535-542. 2013.
13. Imura H, Murata H, Ochi M. Electro-anatomical approach to membranous septal aneurysm: potential as a focus of critical ventricular arrhythmias. Surgical Science 4: 543-546. 2013.
14. Imura H, Hames KY, Miyagi Y, Murata S, Takashi Nitta, Masami Ochi. Ablation on the Mitral Annulus for Treatment of Atrial Fibrillation: Anatomical Consideration to Prevent Coronary Injury. J Arrhythmia 30: 444-445. 2014.

著書

1. Suleiman MS, Imura H. Metabolic differences between pediatric and adult hearts: implications for cardiac surgery. Cardiac Development, (N.M. Ostadal B, Dhalla NS), Boston, Kluwer Academic Publishers. p185-195. 2002
2. Imura H, Ascione R, Angelini GD. Low-frequency Mechanical Ventilation During Cardiopulmonary Bypass. Principles of Pulmonary Protection in Heart Surgery. (Gabriel EA, Salerno T), Springer. p367-75. 2010
3. 白川 真、井村 肇. 呼吸器疾患を有する大動脈疾患の治療. ステントグラフトの大技小技-胸腹部大動脈瘤へのワンランクアップの対処術- (西巻博 田島廣之 加藤正明 岡克彦).株式会社メジカルビュー社pp270-271. 2017.
4. 井村　肇. 人工弁機能不全. Cardiovascular Care Unit, CCU テキスト－循環器救急から集中治療管理まで－(田中啓二・山本剛). 文光堂 p179-185. 2013.
5. 井村　肇. 先天性心疾患 (1)心房中隔欠損症. 循環器内科学. (水野杏一、安武正弘、平山悦之)。シュプリンガー・ジャパン、p266-70. 2010.
6. 井村　肇. 先天性心疾患 (7)大動脈縮窄症. 循環器内科学. (水野杏一、安武正弘、平山悦之)。シュプリンガー・ジャパン、p286-89. 2010.